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Cytomel Uses, Side Effects & Warnings

Cytomel Uses, Side Effects & Warnings

Cessation of therapy is justified in patients who have maintained a normal TSH during those 2 to 8 weeks. Morphologic hypogonadism and nephrosis should be ruled out before the drug is administered. If hypopituitarism is present, the adrenal deficiency must be corrected prior to starting the drug.

  • Monitor for cardiac arrhythmias during surgical procedures in patients with coronary artery disease receiving suppressive Cytomel therapy.
  • It is the most commonly available brand-name version of liothyronine (synthetic T3).
  • This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function.
  • Follow your doctor’s instructions about using this medicine if you are pregnant.

In our latest question and answer, we discuss how to take both Cytomel (liothyronine) and levothyroxine together. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2 to 4% and 15 to 20%, respectively. Cytomel is contraindicated in patients with uncorrected adrenal insufficiency [see Warnings and Precautions (5.3)].


Each category comes with a set of unique symptoms and understanding where you fit can help you determine if you need to switch medications or simply alter your dose. It’s been my experience that many patients who use and react negatively to it, are often reacting to inactive ingredients, especially starch or gelatin. The problem with these inactive ingredients is that certain patients may actually negatively react to them. All medications contain a combination of both active and inactive ingredients. I’ve found that these 10 foods cause the most problems for thyroid patients.

Drug Interactions

Despite T3 medications being stronger, which could potentially cause side effects, more doctors are starting to believe that the old method of relying on T4 isn’t as effective. Both hormones are important, and both play major roles in the body’s metabolism and energy. The thyroid produces more T4 hormone than T3, with majority of the T3 that is produces coming from the body itself converting T4 to T3. It is also important that you consult your doctor prior to start any new medications or supplements, or increasing doses of your other medications, first. That being said, occasionally unusual reactions to this medication may occur, particularly in those given a high dose by their doctor. Overall Cytomel is a very safe drug and rarely do patients experience side effects.

In the treatment of hypothyroidism, while it’s not as common at T4 in the U.S. it is the most effective and assured way to treat the condition. When using T4, the individual simply has to wait for the hormone to convert to T3 for an advantage to be had, but with Cytomel we correct the issue right from the start. T4 can be a great fat loss tool but nowhere near the level of T3.

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